Transfusion reactions — what to watch for

Transfusions are very safe, but reactions can happen. Tell the nurse straight away if, during or soon after, you notice fever or chills, itching or a rash, chest tightness, breathlessness, back pain, or your heart racing. A serious (haemolytic) reaction is treated by stopping the transfusion immediately.

Some reactions are delayed: unexpected anaemia, tiredness or yellowing (jaundice) 5–14 days later can mean a new antibody — let your team know so they can check.

Circulatory overload (too much, too fast) can strain the heart, which is why the rate is slowed for anyone with a very low starting haemoglobin or heart problems. Getting family-member blood irradiated first avoids a rare but serious reaction.